Clomid in Pregnancy
Clomid is a fertility drug for women to cause ovulation. Clomid is taken for 5 days during the menses cycle and if woman becomes pregnant after the cycle then its fine else after 30 days, after careful examination that woman is not pregnant; 5 day medication is started again. All this procedure should be done with consultation of a fertility specialist doctor. If you are pregnant then one should not take Clomid in any case and one should always try not to become pregnant while using Clomid. Clomid using women should also not breast feed.
Clomid can be very dangerous if it is used during pregnancy and due to that it has been categorized in category X in pregnancy as it can cause lot of damage to the fetus. Category X is given to those medicines which can cause a problem to unborn fetus, if it is taken knowingly or mistakenly. Although there is no such study of using of Clomid in pregnant women but basing on the experiments on animals it is highly suggested to not to use Clomid while pregnant. Therefore doctors, who are advising you on using Clomid, must confirm that you are not pregnant. There are a number of tests which doctor must take before restarting Clomid dosage like checking carefully of any pregnancy, ovarian cyst formation or ovarian enlargement. If doctor is satisfied with the results then only next cycle should be started.
In very few of the women(less than 1 %) who used Clomid and became pregnant, fetal abnormalities like Congenital Heart Lesions, Congenital hip, Congenital Gut Lesions, Down Syndrome, Conjoined Twins and Teratomatous Malformation, Club Foot , Dermoid Cyst of Scalp and inguinal Hernia etc were found. In some cases there were neonatal, still birth or fetal death were observed.
As told earlier that no human study of using Clomid during pregnancy has been observed but few experiments on animals were done. Few pregnant rats were orally fed with 1 to 2 mg/kg of Clomid per day resulted in edematous fetuses with bone problems and having hydramnion and were weak. Doses of 8mg/kg per day resulted in the death of fetuses and in some cases delayed parturition. Doses of 40 mg/kg per day resulted in death of the maternal. Few experiments on rabbits were also conducted as they were given 20 mg/kg or 40 mg/kg per day and it resulted in some changes in bone structure of fetuses. Rhesus Monkeys were given 1.5 to 4.5 mg/kg per day but no effect was noted in the offspring.
It is indeed highly suggested not to use Clomid in pregnancy. In case any woman who has taken Clomid mistakenly while being pregnant must immediately consult the doctor.